2016–1986
167 On the Reactivity of α-Trifluoromethylstyrene in Radical Copolymerizations with Various Fluoroalkenes
J. Walkowiak-Kulikowska, F. Boschet, G. Kostov, V. Gouverneur, B. Ameduri
Eur. Polym. J. 2016, 84, 612–621
166 Hydrogen-Bonded Homoleptic Fluoride–Diarylurea Complexes: Structure, Reactivity and Coordinating Power
L. Pfeifer, K. M. Engle, G. W. Pidgeon, H. A. Sparkes, A. L. Thompson, J. M. Brown, V. Gouverneur
J. Am. Chem. Soc. 2016, 138, 13314–13325
165 Ultrafast Click Chemistry with Fluorosydnones
H. Liu, D. Audisio, L. Plougastel, E. Decuypere, D.-A. Buisson, O. Koniev, S. Kolodych, A. Wagner, M. Elhabiri, A. Krzyczmonik, S. Forsback, O. Solin, V. Gouverneur. F. Taran
Angew. Chem. Int. Ed. 2016, 55, 12073–12077
Highlighted as Hot Paper
164 Radiosynthesis of SPECT Tracers Via A Copper Mediated 123I Iodination Of (Hetero)Aryl Boron Reagents
T. C. Wilson, G. McSweeney, S. Preshlock, S. Verhoog, M. Tredwell, T. Cailly, V. Gouverneur
Chem. Commun. 2016, 52, 13277–13280
163 Enhanced Copper-Mediated 18F-fluorination of Aryl boronic esters provides Eight Radiotracers for PET Applications
S. Preshlock, S. Calderwood, S. Verhoog, M. Tredwell, M. Huiban, A. Hienzsch, S. Gruber, T. C. Wilson, N. J. Taylor, T. Cailly, M. Schedler, T. L. Collier, J. Passchier, R. Smits, J. Mollitor, A. Hoepping, M. Mueller, C. Genicot, J. Mercier, V. Gouverneur
Chem. Commun. 2016, 52, 8361–8364
162 Asymmetric 18F-Fluorination for Applications in Positron Emission Tomography
F. Buckingham, V. Gouverneur
Chem. Sci. 2016, 7, 1645–1652
161 18F-Labeling Of Arenes And Heteroarenes For Applications In Positron Emission Tomography
S. Preshlock, M. Tredwell, V. Gouverneur
Chem. Rev. 2016, 116, 719–766
160 Cu-Catalyzed Heteroatom-H bond Insertions with Trifluorodiazoalkanes
S. Hyde, J. Veliks, B. Liégault, D. Grassi, M. Taillefer, V. Gouverneur
Angew. Chem. Int. Ed. 2016, 55, 3785–3789
159 Synthesis and Characterization of a Novel N-F Reagent derived from the Ethano-Troger’s base: 1JFN Coupling constant as Signature for the N-F Bond
R. Pereira, J. Wolstenhulme, G. Sandford, T. D. W. Claridge, V. Gouverneur, J. Cvengroš Chem. Commun. 2016, 52, 1606–1609
158 Ag-Mediated 18F-Labeling of Aryl-CF3 and ArylCHF2 with 18F-Fluoride
S. Verhoog, L. Pfeifer, T. Khotavivattana, S. Calderwood, T. L. Collier, K. Wheelhouse, M. Tredwell, V. Gouverneur
Synlett 2016, 27, 25–28
In celebration of Prof. Steven Ley's 70th birthday
157 Organomediated Enantioselective 18F-Fluorination for PET Applications
F. Buckingham, A. K. Kirjavainen, S. Forsback, A. Krzyczmonik, T. Keller, I. M. Newington, M. Glaser, S. K. Luthra, O. Solin, V. Gouverneur
Angew. Chem. Int. Ed. 2015, 54, 13366–13369
156 [18F]Labeling of Aryl-SCF3, -OCF3 and -OCHF2 with [18F]Fluoride
T. Khotavivattana, S. Verhoog, M. Tredwell, L. Pfeifer, S. Calderwood, K. Wheelhouse, T. L. Collier, V. Gouverneur
Angew. Chem. Int. Ed. 2015, 54, 9991–9995
155 Coordination Diversity in Hydrogen-Bonded Homoleptic Fluoride–Alcohol Complexes Modulates Reactivity
K. M. Engle, L. Pfeifer, G. W. Pidgeon, G. T. Giuffredi, A. L. Thompson, R. S. Paton, J. M. Brown, V. Gouverneur
Chem. Sci. 2015, 6, 5293–5302
154 Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas G. Yang, M. O'Duill, V. Gouverneur, M. P. Krafft
Angew. Chem. Int. Ed. 2015, 54, 8402–8406
Highlighted as Very Important Paper
153 Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl]trimethylsilanes with Aryl Halides M. O'Duill, E. Dubost, L. Pfeifer, V. Gouverneur
Org. Lett. 2015, 17, 3466–3469
152 Oxidative Fluorination of N-Arylsulfonamides
F. Buckingham, S. Calderwood, B. Checa, T. Keller, M.Tredwell, T. L. Collier, I. M. Newington, R. Bhalla, M. Glaser, V. Gouverneur
J. Fluorine Chem. 2015, 180, 33–39
151 Synthesis of 18F-Arenes from Spirocyclic Iodonium(III) Ylides via Continuous-Flow Microfluidics
S. Calderwood, T. Lee Collier, V. Gouverneur, S. H. Liang, N. Vasdev
J. Fluorine Chem. 2015, 178, 249–253
150 A Dual Radiolabelling Approach for Tracking Metal Complexes: Investigating the Speciation of Copper Bis(thiosemicarbazonates) in Vitro and in Vivo
R. Hueting, V. Kersemans, M. Tredwell, B. Cornelissen, M. Christlieb, A. D. Gee, J. Passchier, S. C. Smart, V. Gouverneur, R. J. Muschel, J. R. Dilworth
Metallomics 2015, 7, 795–804
149 Iodine Transfer Copolymerization of fluorinated a-Methylstyrenes with Styrenes using 1-iodoperfluorohexane as the Chain Transfer Agent
J. Walkowiak, A. Szwajca, F. Boschet, V. Gouverneur, B. Ameduri
Macromolecules 2014, 47, 8634–8644
148 A Diversity Oriented Approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH- and CF3(SCF3)CH-Substituted Arenes from 1-(Diazo-2,2,2-trifluoroethyl)arenes
E. Emer, Enrico; J. Twilton, M. Tredwell, S. Calderwood, T. Collier, B. B. Liégault, M. Taillefer, V. Gouverneur
Org. Lett. 2014, 16, 6004–6007
147 Asymmetric Fluorocyclizations of Alkenes
J. Wolstenhulme, V. Gouverneur
Acc. Chem. Res. 2014, 47, 3560–3570
146 Anti-CD20 therapy suppresses focal immune-mediated lesion formation and associated microglial activation in the rat brain
A. Dickens, N. Seneca, Y. Couch, S. Campbell, B. Checa, V. Kersemans, E. Warren, M. Tredwell, N. Sibson, V. Gouverneur, D. Leppert, D. Anthony
Ann. of Clin. and Transl. Neur. 2014, 1, 659–669
145 A General Copper Mediated Nucleophilic 18F-Fluorination of Arenes
M. Tredwell, S. Preshlock, N. Taylor, S. Gruber, M. Huiban, J. Passchier, C. Genicot, J. Mercier, V. Gouverneur
Angew. Chem. Int. Ed. 2014, 53, 7751–7755
144 cis Specific Hydrofluorination of Alkenylarenes under Palladium Catalysis by an Ionic Pathway
E. Emer, L. Pfeifer, J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2014, 53, 4181–4185
143 A Comparison of the Behaviour of 64Cu-acetate and 64Cu-ATSM in vitro and in vivo
R. Hueting, V. Kersemans, B. Cornelissen, M. Tredwell, K. Hussien, M. Christlieb, A. D. Gee, J. Passchier, S. C Smart, J. R Dilworth, V. Gouverneur, R. J. Muschel
J. Nucl. Med. 2014, 55, 128–134
142 Glail Activation in the Early Stages of Brain Metastasis: TSPO as a Diagnostic Biomarker
E. R. O’Brien, V. Kersemans, M. Tredwell, B. Checa, S. Serres, M. S. Soto, V. Gouverneur, D. Leppert, D. C. Anthony, N. R. Sibson
J. Nucl. Med. 2014, 55, 275–280
141 Enhanced Aqueous Suzuki-Miyaura Coupling Allows Site specific Polypeptide [18F]labeling
M. Gao, V. Gouverneur, B. Davis
J. Am. Chem. Soc. 2013, 135, 13612–13615
140 Intramolecular OH⋅⋅⋅FC Hydrogen Bonding in Fluorinated Carbohydrates: CHF is a Better H-Bond Acceptor than CF2
G. T. Giuffredi, V. Gouverneur, B. Bernet
Angew. Chem. Int. Ed. 2013, 52, 10524–10528
139 A Broadly Applicable [18F]Trifluoromethylation of Aryl and Heteroaryl Iodides for PET Imaging
M. Huiban, M. Tredwell, S. Mizuta, Z. Wan, X. Zhang, T. Lee Collier, V. Gouverneur, J. Passchier
Nat. Chem. 2013, 5, 941–944
Highlighted (Perspective) in Science 2013
138 Redox Chemistry of Trifluoromethyl Sulfonium Salts as CF3 Radical Sources
S. Mizuta, S. Verhoog, K. Wheelhouse, V. Gouverneur, M. Medebielle
J. Fluorine Chem. 2013, 155, 124–131
(Special Issue in honor of Prof Ojima ACS Fluorine Award)
137 Asymmetric Electrophilic Fluorocarbocyclization with Carbon Nucleophiles
J. R. Woltenshulme, J. Rosenqvist, O. Lozano, J. Ilupeju, K. M. Engle, G. Pidgeon, P. R. Moore, G. Sandford, V. Gouverneur
Angew. Chem. Int. Ed. 2013, 52, 9796–9800
Highlighted in Chemical and Engineering News
136 Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes
S. Mizuta, I. S. Stenhagen, M. O’Duill, J. Wolstenhulme, A. Kirjavainen, S. Forsback, M. Tredwell, G. Sandford, P. R. Moore, M. Huiban, S. K. Luthra, J. Passchier, O. Solin, V. Gouverneur
Org. Lett. 2013, 15, 2648–2651
Top 10 most downloaded papers June 2013
135 Trifluoromethylation of Allylsilanes under Photoredox Catalysis
S. Satoshi, K. M. Engle, S. Verhoog, O. Galicia-Lopez, M. O’Duill, M. Medebielle, K. Wheelhouse, G. Rassias, A. Thompson, V. Gouverneur
Org. Lett. 2013, 15, 1250–1253
Highlighted by SYNFACTS, P005213SF (Professor Paul Knochel and Andreas K. Steib)
134 Catalytic Hydrotrifluoromethylation of Unactivated Alkenes
S. Mizuta, S. Verhoog, K. M. Engle, T. Khotavivattana, M. O’Duill, K. Wheelhouse, G. Rassias, M. Medebielle, V. Gouverneur
J. Am. Chem. Soc. 2013, 135, 2505–2508
Top 4 most downloaded papers February 2013
Highlighted in Chemical and Engineering News
133 [18F]Fluorination of Arylboronic Ester using [18F]Selectfluor bis(triflate): Application to 6-[18F]Fluoro-L-DOPA
I. S. R. Stenhagen, A. K. Kirjavainen, S. J. Forsback, C. G. Jørgensen, E. G. Robins, S. K. Luthra, O. Solin, V. Gouverneur
Chem. Commun. 2013, 49, 1386–1388
132 Regio- and Stereoretentive Synthesis of Branched, Linear (E)- and (Z)-Allyl Fluorides from Allyl Carbonates under Ir-Catalysis
E. Benedetto, M. Tredwell, C. Hollingworth, T. Khotavivattana, J. M. Brown, V. Gouverneur
Chem. Sci. 2013, 4, 89–96 (Back Cover)
131 [18F]Labeling of Arenes M. Tredwell, V. Gouverneur
Angew. Chem. Int. Ed. 2012, 51, 11426–11438
130 Conformational Analysis of Fluorinated Pyrrolidines using 19F-1H Scalar Couplings and Heteronuclear nOes
L. E. Combettes, P. Clausen-Thue, M. King, B. Odell, A. L. Thompson, V. Gouverneur, T. D. W. Claridge
Chem. Eur. J. 2012, 18, 13133–13141 (Back cover)
129 Synthesis of 3-Fluoropyrrolidines and 4-Fluoropyrrolidin-2-ones from Allylic Fluorides
L. E. Combettes, M. Schuler, R. Patel, B. Bonillo, B. Odell, A. L. Thompson, T. D. W. Claridge, V. Gouverneur
Chem. Eur. J. 2012, 18, 13126–13132 (Back Cover)
128 Trifluoromethylation of Allylsilanes under Copper Catalysis
S. Mizuta, O. Galicia-López, K. M. Engle, S. Verhoog, K. Wheelhouse, G. Rassias, V. Gouverneur
Chem. Eur. J. 2012, 18, 8583–8587
127 Metal Free Oxidative Fluorination of Phenols with [18F]Fluoride
Z. Gao, Y. H. Lim, M. Tredwell, Lei Li, S. Verhoog, M. Hopkinson, W. Kaluza, T. Lee Collier, J. Passchier, M. Huiban, V. Gouverneur
Angew. Chem. Int. Ed. 2012, 51, 6733–6737
126 Metal Free Fluoroamination of Allylsilanes: a Route to 3-Fluoropyrrolidines
L. E. Combettes, O. Lozano and V. Gouverneur
J. Fluorine Chem. 2012, 143, 167–176
(Special issue to honor Prof. D. O' Hagan ACS Creativity Fluorine Chemistry)
125 Palladium-Catalyzed Substitution and Cross-Coupling of Benzylic Fluorides
G. Blessley, P. Holden, M. Walker, J. M. Brown and V. Gouverneur Org. Lett. 2012, 14, 2754–2757
124 Radiochemistry: Flipping Fluoride’s Reactivity
V. Gouverneur
Nat. Chem. 2012, 4, 152–154
123 Platinum Catalysed Substitution of Allylic Fluorides
E. Benedetto, M. Keita, M. Tredwell, C. Hollingworth, J. M. Brown, V. Gouverneur
Organometallics 2012, 31, 1408–1416
122 Transition Metal and Nucleophilic Fluorination
C. Hollingsworth, V. Gouverneur
Chem. Commun. 2012, 48, 2929–2942 (Highlight By Invitation)
121 Hypoxia Imaging Using PET and SPECT; The Effects of Anesthetic and Carrier Gas on [Cu-64]-ATSM, [(99)mTc-HL91 and [F-18]-FMISO Tumor Hypoxia Accumulation
V. Keersemans, B. Cornelissen, R. Hueting, M. Tredwell, J. Dilworth, V. Gouverneur, R. J. Muschel, S. C. Smart
PLOS One 2011, 6, e25911
120 PET F-18 Chemistry
M. Tredwell, V. Gouverneur
J. Labelled Compd. Rad. 2011, 54, 389–390
119 Supported Synthesis of Halogenated Organic Compounds
S. Boldon, I. S. R. Stenhagen, J. E. Moore, S. K. Luthra, V. Gouverneur
Synthesis 2011, 24, 3929–3953
118 A fluorous and click approach for screening potential PET probes: evaluation. of potential hypoxia biomarkers
R. Bejot, L. Carroll, K. Bhakoo, V. Gouverneur
Bioorg. Med. Chem. 2012, 20, 324–329
117 Organocatalyzed Enantioselective Fluorocyclization
O. Lozano, G. Blessley, T. Martinez del Campo, A. L. Thompson, G. T. Giuffredi, M. Bettati, M. Walker, R. Borman, V. Gouverneur
Angew. Chem. Int. Ed. 2011, 50, 8105–8109
117 Facile Synthesis of 4-Deoxy-4-fluoro-a-D-talopyranoside, 4-Deoxy-4-fluoro-a-D-idopyranoside and 2,4-Dideoxy-2,4-difluoro-a-D-talopyranoside
G. T. Giuffredi, L. E. Jennings, B. Bernet, V. Gouverneur
J. Fluorine Chem. 2011, 132, 772–778
(Special Issue in honor of Alain Tressaud)
116 De Novo Synthesis of 4-Deoxy-4,4-Difluoro- and 2,4-Dideoxy-2,4,4-Trifluoro-Hexosides
G. T. Giuffredi, B. Bernet, V. Gouverneur
Eur. J. Org. Chem. 2011, 3825–3836
(Special Issue Women in Chemistry)
115 AuI/AuIII Catalysis: An Alternative Approach for C-C Oxidative Coupling
M. N. Hopkinson, A. D. Gee, V.Gouverneur
Chem. Eur. J. 2011, 17, 8248–8262
114 Palladium-Catalyzed Allylic Fluorination
C. Hollingworth, A. Hazari, M. N. Hopkinson, M. Tredwell, E. Benedetto, M. Huiban, A. D. Gee, J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2011, 50, 2613–2617 (HOT Paper)
113 Convergent 18F Radiosynthesis: A New Dimension for Radiolabeling
Lei Li, M. N. Hopkinson, R. Leuma Yona, R. Bejot, A. D. Gee, V. Gouverneur
Chem. Sci. 2011, 2, 123–131
112 The Chemoselective One-Step Alkylation and Isolation of Thiophosphorylated Cdk2 Substrates in the Presence of Native Cysteine
S. E. Lee, L. M. Elphick, H. B. Kramer, A. M.E. Jones, E. S. Child, A. Anderson, L. Bonnac, N. Suwaki, B. M. Kessler, V. Gouverneur, D. J. Mann
ChemBioChem. 2011, 12, 633–640
111 The Traceless Staudinger Ligation for Indirect 18F-Radiolabelling
L. Carroll, S. Boldon, R. Bejot, J. E. Moore, J. Declerck, V. Gouverneur
Org. Biomol. Chem. 2011, 9, 136–140 (HOT paper)
110 Hypoxia imaging Agents – bis(thiosemicarbazones) beyond the parent Cu(ATSM)
R. Huting, V. Keersemans, M. Tredwell, M. Christlieb, V. Gouverneur, J. Dilworth
Nucl. Med. Biol. 2010, 37, 695–696
109 Gold Catalysis and Fluorine
M. N. Hopkinson, A. D. Gee and V. Gouverneur
Isr. J. Chem. 2010, 50, 675–690
108 Gold-Catalyzed Cascade Cyclization-Oxidative Alkynylation of Allenoates
M. Hopkinson, J. Ross, G. Giuffredi, A. D. Gee, V. Gouverneur
Org. Lett. 2010, 12, 4904–4907
107 Catalytic Enantioselective Synthesis of P-Stereogenic Compounds
J. S. Harvey, V. Gouverneur
Chem. Comm. 2010, 46, 7477–7485 (Feature Article)
106 Radiosynthesis and Evaluation of [18F]Selectfluor bis(triflate)
H. Teare, E.G. Robins, A. Kirjavainen, S. Forsback, G. Sandford, O. Solin, S. K. Luthra, V. Gouverneur
Angew. Chem. Int. Ed. 2010, 49, 6821–6824 (HOT Paper)
105 Gold-Catalyzed Diastereoselective Synthesis of α-Fluoroenones from Propargyl Acetates
M. N. Hopkinson, G. T. Giuffredi, A. D. Gee, V. Gouverneur
Synlett 2010, 18, 2737–2742
104 Batch-mode microfluidic radiosynthesis of N-succinimidyl-4-[18F]fluorobenzoate for protein labeling
R. Bejot, A. M. Elizarov, C. Ball, J. Zhang, R. Miraghaie, H. C. Kolb, V. Gouverneur
J. Label. Compd. Radiopharm. 2010, 54, 117–122
103 Bis(thiosemicarbazones) as bifunctional chelators for the room temperature labelling of peptides and proteins
R. Hueting, M. Christlieb, J. R Dilworth, E. García Garayoa, V. Gouverneur, M. W. Jones, V. Maes, R. Schibli, X. Sun, D. A. Tourwé
Dalton Trans. 2010, 39, 3620–3632 (HOT Paper)
102 Synthesis and O-Phosphorylation of 3,3,4,4-Tetrafluoro-Aryl-C-Nucleoside Analogues
L. Bonnac, S. E. Lee, G. T. Giuffredi, L. M. Elphick, A. A. Anderson, E. S. Child, D. J. Mann, V. Gouverneur
Org. Biomol. Chem. 2010, 8, 1445–1454
101 Diastereoselective Synthesis of P-Stereogenic Heterocycles via Enyne Ring-Closing Metathesis
J. S. Harvey, G. T. Giuffredi, V. Gouverneur
Org. Lett. 2010, 12, 1236–1239
100 Catalytic activation of hydrogen, silicon, and fluorine by transition-metal complexes
W. Rau, A. Hazari, V. Gouverneur
Pure Appl. Chem. 2010, 82, 1415–1428
99 Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [F-18]FMISO as hypoxia-selective tracer for PET
R. Bejot, V. Kersemans, C. Kelly, V. Gouverneur
Nucl. Med. Biol. 2010, 37, 565–575
98 Syntheses of Mono-, Di-, and Trifluorinated Styrenic Monomers J. Walkowiak, T. M. del Campo, B. Ameduri, V. Gouverneur
Synthesis 2010, 11, 1883–1890
97 Orthogonal F-18 and Cu-64 labelling of functionalised bis(thiosemicarbazonato) complexes
L. Carroll, R. Bejot, R. Hueting, V. Gouverneur
Chem. Commun. 2010, 46, 4052–4054 (Cover)
96 Gold-Catalyzed Intramolecular Oxidative Cross-Coupling of Nonactivated Arenes
M. N. Hopkinson, A. Tessier, A. Salisbury, V. Gouverneur
Chem. Eur. J. 2010, 16, 4739–4743
95 Transition-Metal-Mediated Reactions for C(sp2)–F Bond Construction: the State of Play
J. M. Brown, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 8610–8614
94 A New departure in Fluorination Chemistry
V. Gouverneur
Science 2009, 325, 1630–1631
93 Recent Progress in the use of Fluoroorganic Compounds in Pericyclic Reactions
Y-h. Lam, S. J. Stanway, V. Gouverneur
Tetrahedron 2009, 65, 9905–9933
92 Electrophilic Fluorocyclization of Allyl Silanes
S. C. Wilkinson, O. Lozano, M. Schuler, M. Pacheco, R. Salmon, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 7083–7086
91 Oxidative Detagging of Fluorous Organosilanes
S. Boldon, J. E. Moore, V. Gouverneur
J. Fluor. Chem. 2009, 130, 1151-1156
(By Invitation - Issue to celebrate the International Conference on Fluorine Chemistry ’09, Kyoto)
90 Developments in Fluorocyclization Methodologies
S. C. Wilkinson, R. Salmon, V. Gouverneur
Future Med. Chem. 2009, 1, 847–863
(Special Focus: Fluorine in Medicinal Chemistry - By Invitation)
89 Exploring the Roles of Protein Kinases Using Chemical Genetics
L. M. Elphick, S. E. Lee, A. A. Anderson, E. S. Child, L. Bonnac, V. Gouverneur, D. J. Mann
Future Med. Chem. 2009, 1, 1233 (By Invitation)
88 A Quantitative Comparison of Wild Type and Gatekeeper Mutant Cdk2 for Chemical Genetic Studies with ATP Analogues
L. M. Elphick, S. E. Lee, E. S. Child, A. Prasad, C. Pignocchi, S. Thibaudeau, A. A. Anderson, L. Bonnac, V. Gouverneur, D. J. Mann
ChemBioChem. 2009, 10, 1519–1526
87 Synthesis and Reactivity of Novel Phosphate Modified ATP Analogues
S. E. Lee, L. M. Elphick, A. A. Anderson, E. S. Child, D. J. Mann, V. Gouverneur
Bio. Med. Chem. Lett. 2009, 19, 3804–3807 (By Invitation)
86 Asymmetric de novo Synthesis of Fluorinated D-Glucitol and D-Mannitol Analogues
G. T. Giuffredi, S. Purser, M. Sawicki, A. L. Thompson, V. Gouverneur
Tetrahedron Asym. 2009, 20, 910–920 (By Invitation)
85 Phosphine-Catalysed Cyclisation of ß-Hydroxy-a,-a-Difluoroynones
M. Schuler, A. Monney, V. Gouverneur
Synlett 2009, 11, 1733–1736
(Highlighted in SYNFACTS (Issue 9/ p 964)
84 Palladium-Catalyzed Substitution of Allylic Fluorides
A. Hazari, V. Gouverneur, J. M. Brown
Angew. Chem. Int. Ed. 2009, 48, 1296–1299
83 Diels–Alder Exo-Selectivity in Terminal-Substituted Dienes and Dienophiles: Experimental Discoveries and Computational Explanations
Y-h. Lam, P. H-Y. Cheong, J. M. Blasco Mata, S. J. Stanway, V. Gouverneur, K. N. Houk
J. Am. Chem. Soc. 2009, 131, 1947–1957
82 Enantioselective Synthesis of P-Stereogenic Phosphinates and Phosphine Oxides by Mo-Catalyzed Asymmetric Ring-Closing Metathesis
J. S. Harvey, S. J. Malcolmson, K. S. Dunne, S. J. Meek, A. L. Thompson, R. R. Schrock, A. H. Hoveyda, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 762–766
(Highlighted in SYNFACTS (Issue 4/ p 397)
81 Fluorous Synthesis of 18F-Radiotracers with [18F] Fluoride ion: Nucleophilic Fluorination as the Detagging Process
R. Bejot, T. Fowler, L. Carroll, S. Boldon, J. E. Moore, J. Declerck, V. Gouverneur
Angew. Chem. Int. Ed. 2009, 48, 586–589
80 A Two-Directional Approach to Enantiopure 1,4-Difluoro-Cyclohexenes: Synthesis of Difluorinated Cyclitol Analogues
S. Purser, T. D. W. Claridge, B. Odell, P. R. Moore, V. Gouverneur Org. Lett. 2008, 10, 4263–4266
79 Gold(I)-Catalyzed Alkoxyhalogenation of Hydroxy-Difluoroynones
M. Schuler, F. Silva, C. Bobbio, A. Tessier, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47, 7927–7930
78 Fluorous Synthesis of Allylic Fluorides: C–F bond Formation as the Detagging Process
S. Boldon, J. E. Moore, V. Gouverneur
Chem. Commun. 2008, 31, 3622–3624
77 The Chemistry of Propargylic and Allylic Fluorides
M. Pacheco, S. Purser, V. Gouverneur
Chem. Rev. 2008, 108, 1943–1981
76 First Examples of Molecularly Imprinted Nanogels with Aldolase Type I Activity
D. Carboni, K. Flavin, A. Servant, V. Gouverneur, M. Resmini
Chem. Eur. J. 2008, 14, 7059–7065
75 Stereospecific anti SE2' Fluorination of Allenylsilanes: Synthesis of Enantioenriched Propargylic Fluorides
L. Carroll, S. McCullough, T. Rees, T. D. W. Claridge, V. Gouverneur Org. Biomol. Chem. 2008, 6, 1731–1733
74 Fluorine-Directed Diastereoselective Iodocyclisations
M. Tredwell, J. A. R. Luft, M. Schuler, K. Tenza, K. N. Houk, V. Gouverneur
Angew. Chem. Int. Ed. 2008, 47, 357–360 (Selected by the Editor as a Hot Article)
73 Fluorine in Medicinal Chemistry
S. Purser, P. R. Moore, S. Swallow and V. Gouverneur
Chem. Soc. Rev. 2008, 37, 320–330 (Tutorial Review)
72 Diastereoselective Fluorination of Silylated 1,2-Oxazines to Access Fluorinated N,O-Heterocycles
Y.-h. Lam, M. N. Hopkinson, S. J. Stanway, V. Gouverneur
Synlett 2007, 19, 3022–3027
71 Single and Double Stereoselective Fluorination of (E)-Allylsilanes M. Sawicki, A. Kwok, M. Tredwell and V. Gouverneur
Beilstein J. Org. Chem. 2007, 3, 34
(Thematic Issue on Contemporary Organosilicon Chemistry, By Invitation)
70 A Concise Synthesis of Enantioenriched Fluorinated Carbocycles
Y.-h. Lam, C. Bobbio, I. R. Cooper, V. Gouverneur
Angew. Chem. Int. Ed. 2007, 46, 5106–5110. (Highlighted as a Frontispiece and SYNFORM story)
69 Kinetics of Radical Copolymerisation of [1-(Fluoromethyl)vinyl]benzene with Chlorotrifluoroethylene
G. Kostov, M. Tredwell, V. Gouverneur, B. Ameduri
J. Poly. Sci. Part A: Polymer Chem. 2007, 45, 3843–3850
68 Using Chemical Genetics and ATP Analogues to Dissect Protein Kinase Function
L. M. Elphick, S. E. Lee, V. Gouverneur, D. J. Mann
ACS Chem. Biol. 2007, 2, 299–314
67 Synthesis and Reactivity of [18F]N-Fluorobenzenesulfonimide
H. Teare, E. G. Robins, E. Årstad, S. K. Luthra, V. Gouverneur
Chem. Commun. 2007, 23, 2330–2332 (Front Cover)
66 Highly Diastereoselective Electrophilic Fluorination of Cyclic Syn b-Hydroxysilanes
S. Purser, C. Wilson, P. R. Moore, V. Gouverneur
Synlett 2007, 7, 1166–1168
65 A Convergent Approach for the Synthesis of fluorinated Sphingosine Analogues
H. Teare, F. Huguet, M. Tredwell, S. Thibaudeau, S. K. Luthra, V. Gouverneur
Arkivoc 2007, 10, 232–244
(commemorative Issue for Professor A. Krief, By Invitation)
64 Enantioselective Organocatalytic Aldol reaction of Ynones and its Synthetic Applications
F. Silva, M. Sawicki, V. Gouverneur
Org. Lett. 2006, 8, 5417–5419
63 Pd(II)-Catalysed CascadeWacker-Heck Reaction: Chemoselective Coupling of Two Electron Deficient Reactants
F. Silva, M. Reiter, R. Mills-Webb, M. Sawicki, D. Klär, N. Bensel, A. Wagner, V. Gouverneur
J. Org. Chem. 2006, 71, 8390–8394
62 Homometathesis and Cross-Metathesis Coupling of Phosphino-Borane Templates with Electron-rich and electron-Poor Olefins
K. S. Dunne, S. E. Lee, V. Gouverneur
J. Organometal. Chem. 2006, 69, 5246–5259
61 Enantioselective Synthesis of a Key “A Ring” Intermediate for the preparation of 1-alpha-Fluoro Vitamin D3 Analogues
G. Giuffredi, C. Bobbio, V. Gouverneur
J. Org. Chem. 2006, 5361–5364
60 Synthesis and Synthetic Applications of Allylic monofluorides M. Pacheco, V. Gouverneur
Chemistry Today 2006, 24, 12–16
59 Catalytic Asymmetric Fluorinations
C. Bobbio, V. Gouverneur
Org. Biomol. Chem. 2006, 4, 2065–2075 (Inside Cover)
58 Synthesis of Propargylic Fluorides from Allenylsilanes
L. Carroll, L. Garcia, M. C. Pacheco, V. Gouverneur
Chem. Commun. 2006, 39, 4113–4115
57 Sequential Desymmetrization-Fluorination: Enantioselective synthesis of fluorinated Cyclitols
S. Purser, P. Moore, V. Gouverneur
Chem. Eu. J. 2006, 12, 9176–9185
56 Intramolecular Hetero-Michael Addition of b-Hydroxyenones for the Preparation of Highly Substituted Tetrahydropyranones
M. Reiter, H. Turner, V. Gouverneur
Chem. Eu. J. 2006, 12, 7190–7203
55 Electrophilic Fluorination of Organosilanes
M. Tredwell, V. Gouverneur
Org. Biomol. Chem 2006, 4, 26–32 (Featured in Chemical Science)
54 Diastereoselective Ring-Closing Metathesis: Synthesis of P-Stereogenic Phosphinates from Prochiral Phosphinic Acid Derivatives
K. S. Dunne, F. Bisaro, B. Odell, J-M, Paris, V. Gouverneur
J. Org. Chem. 2005, 70, 10803–10809
53 Elongation of ß-Hydroxyenones by Cross-Metathesis
F. Silva, V. Gouverneur
Tetrahedron Lett. 2005, 50, 8705–8709
52 Synthesis of Novel Enantiopure Fluorinated Building Blocks from Acyclic Chiral Allylsilanes
M. Tredwell, K. Tenza, M. Pacheco, V. Gouverneur
Org. Lett. 2005, 7, 4495–4497
51 Palladium-Catalyzed Oxidative Cyclizations: Synthesis of Dihydropyranones and Furanones
M. Reiter, H. Turner, R. Mills-Webb, V. Gouverneur
J. Org Chem. 2005, 70, 8478–8485
50 Biocatalytic Approaches to Hetero Diels-Alder Adducts of Carbonyl Compounds
V. Gouverneur, M. Reiter
Chem. Eur. J. 2005, 11, 5806–5815 (Frontispiece)
49 Electrophilic Fluorodesilylation of Allenylmethylsilanes: a Novel Entry to 2-Fluoro-1,3-dienes
M. Pacheco, V. Gouverneur
Org. Lett. 2005, 7, 1267–1270
48 Desymmetrization by Direct Cross-metathesis Producing Hitherto Unreachable P-stereogenic phosphine oxides
F. Bisaro, V. Gouverneur
Tetrahedron 2005, 61, 2395–2400
47 A Catalytic Asymmetric Bioorganic Route to Enantioenriched Tetrahydro- and Dihydropyranones
C. Baker-Glenn, N. Hodnett, M. Reiter, S. Ropp, R. Ancliff, V. Gouverneur
J. Am. Chem. Soc. 2005, 127, 1481–1486
46 A Biocatalytic Route to Enantioenriched Sulfanyl Aldol Products C. Baker-Glenn, R. Ancliff, V. Gouverneur
Tetrahedron 2004, 60, 7607–7619
45 Oxidative Cyclization of Hydroxyenones with Palladium(II): A Novel Entry to 2,3-Dihydro-4H-pyran-4-ones
M. Reiter, S. Ropp, V. Gouverneur
Org. Lett. 2004, 6, 91–94
44 Stereoselective Synthesis of Internal Allylic Fluorides
S. Thibaudeau, R. Fuller, V. Gouverneur
Org. Biomol. Chem. 2004, 2, 1110–1112
43 Unusual Reversal of Regioselectivity in Antibody-Mediated Aldol Additions with Unsymmetrical Methyl Ketones
V. Maggiotti, S. Bahmanyar, M. Reiter, M. Resmini, K. N. Houk, V. Gouverneur
Tetrahedron 2004, 60, 619–632
42 Sequential Cross-Metathesis/Electrophilic Fluorodesilylation: a Novel Entry to Functionalized Allylic Fluorides
S. Thibaudeau, V. Gouverneur
Org. Lett. 2003, 5, 4891–4893
41 Synthesis of Unprotected and Borane-Protected Cyclic Phosphines using Ru and Mo based Olefin Metathesis Catalysts
C. A. Slinn, A. J. Redgrave, S. L. Hind, C. Edlin, S. P. Nolan, V. Gouverneur
Org. Biomol. Chem. 2003, 1, 3820– 3825.
40 Cross-metathesis, a Versatile Synthetic Methodology for the Construction of Alkenyl Phosphine Oxides and Bis-phosphine Oxides
F. Bisaro, V. Gouverneur
Tetrahedron Lett. 2003, 44, 7133–7135
39 Regio- and Enantioselective Synthesis of Allylic Fluorides by Electrophilic Fluorodesilylation of Allylsilanes
B. Greedy, J.-M. Paris, T. Vidal, V. Gouverneur
Angew. Chem. Int. Ed. 2003, 42, 3291–3294.
38 Asymmetric Synthesis of Aldol Products Derived from Unsymmetrical Ketones: Assignment of the Absolute Configuration of Antibody Aldol Products
V. Maggiotti, J.-B. Wong, R. Razet, A. R. Cowley, V. Gouverneur
Tetrahedron: Asymmetry 2002, 13, 1789–1798
37 A New Access to Various Functionalized Trimethylsilyl Substituted Carbo- and Heterocycles
M. Schuman, V. Gouverneur
Tetrahedron Lett. 2002, 43, 3513–3516
36 Unprecedented Regiocontrol using an Aldolase I Antibody V. Maggiotti, M. Resmini, V. Gouverneur
Angew. Chem. Int. Ed. Engl. 2002, 41, 1012–1015
35 Synthetic Applications of Electrophilic Fluorodesilylation
V. Gouverneur, B. Greedy
Chem. Eur. J. 2002, 8, 766–772 (Frontispiece)
34 Design and Synthesis of Haptens for the Dynamic Kinetic Resolution of Oxazolin-5-ones
A. Briot, M. Bujard, V. Gouverneur, C. Mioskowski
Eur. J. Org Chem. 2002, 1, 139–144
33 Synthesis of a Novel Diarylphosphinic Acid: a Distorted Ground State Mimic and Transition State Analogue for Amide Hydrolysis
M. Schuman, X. Lopez, M. Karplus, V. Gouverneur
Tetrahedron 2001, 57, 10299–10307
32 Synthesis of a Novel fused alpha,beta-Bispyrone
M. Smietana, V. Gouverneur, C. Mioskowski
Synlett 2001, 10, 1547–1649
31 Fluorodesilylation of Alkenyltrimethylsilanes: a New Route to Fluoroalkenes and Difluoromethyl-substituted Amides, Alcohols or Ethers
B. Greedy, V. Gouverneur
Chem. Commun. 2001, 3, 233–234
30 Novel Synthesis of Borane Complexes of Cyclic Phosphine Using Ruthenium-Catalysed Olefin Metathesis
M. Schuman, M. Trevitt, A. Redd, V. Gouverneur
Angew. Chem. Int. Engl. 2000, 39, 2491–2493.
29 Improvement in Olefin Metathesis using a New Generation of Ruthenium Catalyst Bearing a Imidazolydene Ligand: Synthesis of Heterocycles
M. Bujard, A. Briot, V. Gouverneur, S. Nolan, C. Mioskowski
Org. Lett. 2000, 11, 1517–1519
28 Ring-Closing Metathesis for the Synthesis of Phosphorus Containing Heterocycles
L. Hetherington, B. Greedy, V. Gouverneur
Tetrahedron 2000, 56, 2053–2060
27 Nozaki-Hiyama Reactions on Halogenated Allylchromium Reagents, a New Entry for the Preparation of Quaternary Halogenated Carbons
R. Baati, V. Gouverneur, C. Mioskowski
J. Org. Chem. 2000, 65, 1235–1238
26 An Improved Synthesis of Iodohydrins from Alkenes
M. Smietana, V. Gouverneur, C. Mioskowski
Tetrahedron Lett. 2000, 41, 193–196
25 Ring Closing Metathesis of Phenyl-Substituted Dienes
M. Bujard, A. Briot, V. Gouverneur, C. Mioskowski
Tetrahedron Lett. 1999, 40, 8785–8788
24 A New Approach to the Synthesis of Efaroxan
K. Couture, V. Gouverneur, C. Mioskowski
Bioorg. & Med. Chem. 1999, 9, 3023–3026
23 A Novel Access to Alicyclic Phosphine Oxides via Ring Closing Metathesis
M. Trevitt, V. Gouverneur
Tetrahedron Lett. 1999, 41, 7333–7336
22 An Improved Methodology for the Synthesis of Amidines using Thioimidic Esters
R. Baati, V. Gouverneur, C. Mioskowski
Synthesis 1999, 6, 927–929
21 A Highly Efficient and Practical Synthesis of Cyclic Phosphinates using Ring-Closing Metathesis
M. Bujard, V. Gouverneur, C. Mioskowski
J. Org. Chem. 1999, 64, 2119–2123
20 A New Approach to the Synthesis of Spirooxazolinones
M. Smietana, V. Gouverneur, C. Mioskowski
Tetrahedron Lett. 1999, 40, 1291–1294
19 New Acylnitroso Compounds for the Asymmetric Oxyamination of Dienes
V. Gouverneur, S. J. McCarthy, D. Belotti, C. Mineur, L. Ghosez
Tetrahedron 1998, 54, 10537–10554
18 Total Synthesis of Halomon
T. Schlama, R. Baati, V. Gouverneur, A. Valleix, C. Mioskowski, J.P. Falck
Angew. Chem. Int. Engl. 1998, 37, 2085–2087
17 Tetraethylammonium Trichloride, a New and Versatile Reagent for Chlorination and Oxidation
T. Schlama, K. Gabriel, V. Gouverneur, C. Mioskowski
Angew. Chem. Int. Engl. 1997, 36, 2342–2344
16 One-Step Synthesis of Chiral Guanidinium Salts from Phosgeniminium Salts
T. Schlama, V. Gouverneur, A. Valleix, A. Greiner, L. Toupet, C. Mioskowski
J. Org. Chem. 1997, 62, 4200–4202
15 One-Step Conversion of Protected Alcohols into Alkyl Halides using Dimethylphosgeniminium Salt
T. Schlama, V. Gouverneur, C. Mioskowski
Tetrahedron Lett. 1997, 38, 3517–3520
14 A new and Efficient Preparation of Carbodiimides from Ureas Using Dimethylphosgeniminium Chloride as a Dehydrating Agent T. Schlama, V. Gouverneur, C. Mioskowski
Tetrahedron Lett. 1996, 37, 7047–7048
13 N-Hydroxy-Amino Phosphonate Derivatives as Potential Haptens For Eliciting Catalytic Antibodies
V. Gouverneur, M-N. Lalloz
Tetrahedron Lett. 1996, 37, 6331–6334
12 X-Ray Structure of N-(1'S-hydroxy-4'R-cyclohex-2'-en)-2,5-bis(methoxymethyl)-pyrrolidino carboxamide
J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg. 1996, 6, 359–360
11 X-Ray Structure of trans-(2,5)-bis(methoxymethyl)pyrrolidinocarbohydroxamic acid
B. Tinant, J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg. 1996, 4, 185
10 X-Ray Structure of 3-(3',4'-dimethoxy)-2,6-triphenyl-1-oxa-2,5-diaza-4-oxo-cyclohexane
B. Tinant, J. Feneau-Dupont, J. P. Declercq, V. Gouverneur
Bull. Soc. Chim. Belg. 1996, 4, 215
9 Electrophilic Amination of 2-Aza-1,3-Dienes
V. Gouverneur, L. Ghosez
Tetrahedron 1996, 7585–7598
8 Synthesis and Structural Studies of 2-Aza-1,3-Dienes
L. Ghosez, P. Bayard, P. Nshimyumukiza, V. Gouverneur, F. Sainte, R. Beaudegnies, A. M. Frisque-Hesbain, C. Wynants
Tetrahedron 1995, 51, 11021
7 Antibody Catalysis of Disfavored Diels-Alder Reaction, Control of the Exo and Endo Pathways of the Diels-Alder Reaction by Antibody Catalysis
V. Gouverneur, K. N. Houk, B. D. Pascual-Teresa, B. Beno, K. D. Janda, R. A. Lerner
Organic Chemistry 1993, 6, 292–295
6 Control of the exo and endo Pathways of the Diels-Alder Reaction by Antibody Catalysis
V. Gouverneur, K. N. Houk, B. de Pascual-Teresa, B. Beno, K. D. Janda, R. A. Lerner
Science 1993, 262, 204–208
5 Chiral Amides in Asymmetric Synthesis
L. Ghosez, C. Genicot, V. Gouverneur
Pure & Appl. Chem. 1992, 64, 1849–1856
4 Asymmetric Diels-Alder Reactions of a Nitroso Compound derived from D-Bornane-10,2-Sultam
V. Gouverneur, G. Dive, L. Ghosez
Tetrahedron Asymmetry 1991, 2, 1173–1176
3 Asymmetric Amination of Carboxylic Acids via a Diels-Alder Strategy
V. Gouverneur, L. Ghosez
Tetrahedron Lett. 1991, 32, 5349–5352
2 Stereoselective Diels-Alder Reactions of a new Chiral Carbamoyl Nitroso Compound
V. Gouverneur, L. Ghosez
Tetrahedron Asymmetry 1990, 1, 363–366
1 Synthesis and Reactions of 3-Alkoxy-2H-Azirines
L. Ghosez, F. Sainte, M. Rivera, C. Bernard-Henriet, V. Gouverneur
Recl. Trav. Chim. Pays-Bas 1986, 456–460
